Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 19/20 | 0.42 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17134706 | 0.89 | FASN (0.42) | FASN | |
| SCHEMBL17134624 | 0.88 | FASN (0.42) | FASNPRSS12 | |
| SCHEMBL17134832 | 0.88 | FASN (0.43) | FASNPRSS12 | |
| SCHEMBL17184249 | 0.88 | FASN (0.41) | FASNPRSS12 | |
| SCHEMBL17134854 | 0.86 | MAPT (0.48) | FASN | |
| SCHEMBL17134613 | 0.86 | FASN (0.41) | FASNPRSS12 | |
| SCHEMBL17135212 | 0.85 | FASN (0.40) | FASNPRSS12 | |
| SCHEMBL17135140 | 0.85 | KCNH2 (0.41) | FASNPRSS12 | |
| SCHEMBL17135024 | 0.85 | FASN (0.39) | FASNPRSS12 | |
| SCHEMBL17134668 | 0.85 | FASN (0.39) | FASNPRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2927214-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2015-10-07 | — | — | EP | disclosed |