SCHEMBL1713614

SCHEMBL1713614

C[C@@H](c1ccccc1)N1C[C@@H](C(=O)O)CC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 1.00
MAPT P10636 2/20 0.66
MAPK1 P28482 1/20 0.65
ALOX15 P16050 1/20 0.53
CASP1 P29466 1/20 0.49
CASP7 P55210 1/20 0.49
POLB P06746 2/20 0.48
PTPN1 P18031 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.43
RECQL P46063 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14659880 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL1713616 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL12316010 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL27626477 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL739575 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL1263214 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL523698 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL3659883 1.00 KMT2A (1.00) KMT2AMAPTMAPK1ALOX15CASP1
SCHEMBL522714 0.90 KMT2A (0.81) KMT2AMAPTMAPK1ALOX15POLB
SCHEMBL522715 0.90 KMT2A (0.81) KMT2AMAPTMAPK1ALOX15POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3237903-B1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS EXXONMOBIL RES & ENG CO (US) 2020-02-26 EP claimed
EP-3237903-A1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS Exxonmobil Research And Engineering Company (US) 2017-11-01 EP claimed
US-20160187314-A1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US claimed
WO-2016106211-A1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 WO claimed
US-20160187315-A1 METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US claimed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-3237903-B1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS EXXONMOBIL RES & ENG CO (US) 2020-02-26 EP disclosed
US-20170152258-A9 Substituted Pyridopyrazines as Syk Inhibitors HUTCHISON MEDIPHARMA LIMITED (CN) 2017-06-01 US disclosed
US-20160187314-A1 METHODS FOR AUTHENTICATION AND IDENTIFICATION OF PETROLEUM PRODUCTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US disclosed
US-20160187315-A1 METHODS FOR DETERMINING CONDITION AND QUALITY OF PETROLEUM PRODUCTS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2016-06-30 US disclosed
US-20160002221-A1 Substituted Pyridopyrazines as Syk Inhibitors HUTCHISON MEDIPHARMA LTD (CN) 2016-01-07 US disclosed
EP-2928888-A1 SUBSTITUTED PYRIDOPYRAZINES AS SYK INHIBITORS Hutchison Medipharma Limited (CN) 2015-10-14 EP disclosed
CN-1764456-A Treatment of related diseases using full alpha-7 nACh receptor agonists PHARMACIA & UPJOHN CO LLC (US) 2006-04-26 CN disclosed
US-5864039-A THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1999-01-26 US disclosed
EP-0774460-A1 BENZOIC ACID COMPOUND AND USE THEREOF AS MEDICINE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-05-21 EP disclosed
US-5281612-A Naphthyridine antibacterial agents WARNER-LAMBERT COMPANY (US) 1994-01-25 US disclosed
US-4771054-A QUINOLINE CARBOXYLIC ACID WARNER-LAMBERT COMPANY (US) 1988-09-13 US disclosed
US-4665079-A QUINOLINE DERIVATIVES WARNER-LAMBERT COMPANY (US) 1987-05-12 US disclosed
US-4638067-A NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS WARNER-LAMBERT CO. (US) 1987-01-20 US disclosed
EP-0153163-A2 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds WARNER-LAMBERT COMPANY (US) 1985-08-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160002221-A1 Substituted Pyridopyrazines as Syk Inhibitors SYK, BTK, LYN KMT2A 597/4885MAPT 3971/4885MAPK1 935/4885
US-20170152258-A9 Substituted Pyridopyrazines as Syk Inhibitors SYK, BTK, LYN KMT2A 597/4885MAPT 3971/4885MAPK1 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.