Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL17136337

Cc1cc2ccccc2[n+](C)c1C.N

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.40
PTPN1 P18031 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
RAB9A P51151 1/20 0.37
ACHE P22303 6/20 0.36
NPC1 O15118 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
APOBEC3A P31941 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
BCHE P06276 1/20 0.33
BRD4 O60885 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL4389500 0.96 PTPN1 (0.42) ATMPTPN1KMT2AMEN1RAB9A
SCHEMBL29464772 0.77 ATM (0.56) ATMKMT2AMEN1RAB9AACHE
SCHEMBL278568 0.77 ATM (0.56) ATMKMT2AMEN1RAB9AACHE
SCHEMBL16853932 0.75 ATM (0.40) ATMKMT2AMEN1RAB9AACHE
SCHEMBL244855 0.75 ATM (0.61) ATMKMT2AMEN1RAB9ANPC1
Iodide SCHEMBL30211080 0.75 ATM (0.54) ATMKMT2AMEN1RAB9AACHE
Hydrochloric Acid SCHEMBL11211685 0.75 ATM (0.54) ATMKMT2AMEN1RAB9AACHE
Iodide SCHEMBL11862696 0.75 ATM (0.54) ATMKMT2AMEN1RAB9AACHE
Bromide SCHEMBL11593076 0.75 ATM (0.54) ATMKMT2AMEN1RAB9AACHE
Iodide SCHEMBL8603379 0.75 ATM (0.54) ATMKMT2AMEN1RAB9AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150284683-A1 METHOD, COMBINATION AND/OR COMPOSITION FOR INDUCING CARDIOMYOCYTE DIFFERENTATION SINGAPORE HEALTH SERVICES PTE LTD (SG) 2015-10-08 US disclosed