SCHEMBL17138152

SCHEMBL17138152

CCCCCCCC(=O)Oc1cc(OC(=O)CCCCCCC)c2ccccc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.49
PPARA Q07869 2/20 0.49
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 1/20 0.47
RECQL P46063 1/20 0.47
POLM Q9NP87 1/20 0.46
POLK Q9UBT6 1/20 0.46
POLL Q9UGP5 1/20 0.46
POLH Q9Y253 1/20 0.46
ALOX15 P16050 1/20 0.46
TOP2A P11388 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
CETP P11597 1/20 0.43
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CA2 P00918 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9342126 0.85 KDM4E (0.51) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL3182300 0.84 PPARG (0.60) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL32684916 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL29122753 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL28380496 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL3740934 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL2023424 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL8015856 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL32684946 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E
SCHEMBL28381119 0.83 POLM (0.56) PPARGPPARAKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106309421-A Medical compound and cosmetic compound 沃凯索法株式会社 2017-01-11 CN claimed
CN-106309421-A Medical compound and cosmetic compound 沃凯索法株式会社 2017-01-11 CN disclosed
CN-103800313-B pharmaceutical composition and cosmetic composition 沃凯索法株式会社 2016-09-14 CN disclosed
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 PPARG 1716/4885PPARA 1509/4885KMT2A 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.