SCHEMBL17138174

SCHEMBL17138174

CCCCCCCC(=O)Oc1cccc(OC(=O)CCCCCCC)c1OC(=O)CCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLM Q9NP87 2/20 0.62
POLK Q9UBT6 2/20 0.62
POLL Q9UGP5 2/20 0.62
POLH Q9Y253 2/20 0.62
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
RECQL P46063 1/20 0.56
ALOX15 P16050 1/20 0.51
PPARG P37231 2/20 0.48
LMNA P02545 2/20 0.47
TOP2A P11388 2/20 0.47
PPARA Q07869 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
ATM Q13315 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15558619 0.94 POLM (0.56) POLMPOLKPOLLPOLHMEN1
SCHEMBL15548599 0.94 POLM (0.56) POLMPOLKPOLLPOLHMEN1
SCHEMBL15547852 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15558699 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15550078 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15547677 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15558966 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15547048 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15548748 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1
SCHEMBL15558509 0.93 POLM (0.55) POLMPOLKPOLLPOLHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF RNS CO.,LTD. (KR) 2015-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150283051-A1 DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF HRH3, CBR3, H1-0 POLM 2724/4885POLK 1432/4885POLL 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.