SCHEMBL17142227

SCHEMBL17142227

CCN(c1ccc2c(=O)[nH][nH]c(=O)c2c1)C(C)N

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.54
▸ TDP1 Q9NUW8 1/20 0.52
▸ AR P10275 6/20 0.41
▸ IGLV6-57 P01721 1/20 0.41
▸ GRK6 P43250 1/20 0.35
▸ PARP15 Q460N3 4/20 0.33
▸ PARP10 Q53GL7 4/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ ELANE P08246 1/20 0.33
▸ DAO P14920 1/20 0.32
▸ APAF1 O14727 1/20 0.31
▸ CASP3 P42574 1/20 0.31
▸ CASP6 P55212 1/20 0.31
▸ SENP8 Q96LD8 1/20 0.31
▸ SENP7 Q9BQF6 1/20 0.31
▸ SENP6 Q9GZR1 1/20 0.31
▸ IP6K1 Q92551 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5180879 0.84 KDM4E (0.50) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL17142228 0.82 KDM4E (0.50) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL17142184 0.80 KDM4E (0.51) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL3780116 0.77 KDM4E (0.68) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL3075296 0.73 KDM4E (0.80) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL12909466 0.72 KDM4E (0.62) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL9244286 0.72 KDM4E (0.67) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL12955561 0.71 KDM4E (0.66) KDM4ETDP1ARIGLV6-57PARP15
SCHEMBL11275361 0.71 KDM4E (0.60) KDM4ETDP1ARIGLV6-57GRK6
SCHEMBL5567066 0.70 KDM4E (0.75) KDM4ETDP1ARIGLV6-57GRK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129783-B1 USE OF ABSORBENT PARTICLES FOR IMPROVING SIGNAL DETECTION IN AN ANALYSIS METHOD BIO RAD EUROPE GMBH (CH) 2021-06-02 — — EP disclosed
EP-3129782-B1 CONTROL MARKER FOR IMPLEMENTING METHODS OF ANALYSIS ON SPOTS BIO RAD EUROPE GMBH (CH) 2021-01-06 — — EP disclosed
EP-3129784-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129783-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3129782-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS Bio-Rad Innovations (FR) 2017-02-15 — — EP disclosed
EP-3126832-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS Bio-Rad Innovations (FR) 2017-02-08 — — EP disclosed
WO-2015155254-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155248-A1 USE OF A COLORANT IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015155255-A1 USE OF ABSORBENT PARTICLES IN ORDER TO IMPROVE SIGNAL DETECTION IN AN ANALYSIS METHOD BIO-RAD INNOVATIONS (FR) 2015-10-15 — — WO disclosed
WO-2015150583-A1 CONTROL MEANS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD INNOVATIONS (FR) 2015-10-08 — — WO disclosed
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