Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CCR1 | P32246 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693305 | 1.00 | PTGDR2 (0.75) | PTGDR2MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL27712896 | 1.00 | PTGDR2 (0.75) | PTGDR2MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL1714242 | 0.90 | PTGDR2 (0.75) | PTGDR2CCR1 | |
| SCHEMBL4607656 | 0.89 | PTGDR2 (0.90) | PTGDR2CCR1 | |
| SCHEMBL27693218 | 0.89 | PTGDR2 (0.60) | PTGDR2MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL27712889 | 0.88 | PTGDR2 (0.60) | PTGDR2MEN1ALOX15KMT2ASMN1; SMN2 | |
| SCHEMBL27693394 | 0.87 | PTGDR2 (0.58) | PTGDR2MEN1ALOX15TSHRMAPK1 | |
| SCHEMBL4941310 | 0.86 | PTGDR2 (1.00) | PTGDR2CCR1 | |
| SCHEMBL1713552 | 0.85 | PTGDR2 (0.78) | PTGDR2CCR1 | |
| SCHEMBL27727369 | 0.85 | PTGDR2 (0.75) | PTGDR2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-B1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2011-07-20 | — | — | EP | claimed |
| CN-101107226-A | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | CN | claimed |
| CN-101107226-A | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2008-01-16 | — | — | CN | disclosed |