Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490381 | 0.78 | KDM4E (0.39) | P4HTMALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31692110 | 0.70 | NQO1 (0.59) | P4HTMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL18589251 | 0.65 | CYP4F2 (0.48) | P4HTMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL1403507 | 0.65 | P4HTM (0.63) | P4HTMALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL28370402 | 0.63 | MEN1 (0.47) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5104455 | 0.62 | KMT2A (0.46) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL34470178 | 0.62 | IKBKE (0.43) | P4HTMALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL34470138 | 0.61 | DHODH (0.42) | P4HTMALDH1A1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5104753 | 0.61 | KMT2A (0.45) | ALDH1A1MAPTKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18496839 | 0.60 | P4HTM (0.47) | P4HTMALDH1A1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426120-A1 | Pyridyltetrahydropyridines and pyridylpiperidines, and method of manufacturing them | Fujifilm Finechemicals Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |