Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.58 |
| ▸ | STAT6 | P42226 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.49 |
| ▸ | SCTR | P47872 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17143921 | 0.93 | FLT3 (0.55) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17150841 | 0.93 | FLT3 (0.55) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144357 | 0.83 | FLT3 (0.57) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144359 | 0.83 | FLT3 (0.57) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144385 | 0.83 | FLT3 (0.62) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144384 | 0.83 | FLT3 (0.62) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144607 | 0.83 | FLT3 (0.56) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144606 | 0.83 | FLT3 (0.56) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17150842 | 0.83 | FLT3 (0.56) | FLT3STAT6CDK1CCNB2CCNE2 | |
| SCHEMBL17144400 | 0.81 | FLT3 (0.54) | FLT3STAT6CDK1CCNB2CCNE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015151006-A1 | SUBSTITUTED PURINE COMPOUNDS AS BTK INHIBITORS | LUPIN LIMITED (IN) | 2015-10-08 | — | — | WO | disclosed |