SCHEMBL17145388

SCHEMBL17145388

CC[C@H]1OC(O)[C@H](OCc2ccccc2)[C@@H](C)[C@@H]1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.40
MTOR P42345 1/20 0.40
SLC6A2 P23975 1/20 0.38
TNF P01375 1/20 0.37
TACR2 P21452 3/20 0.36
PDE4D Q08499 1/20 0.36
SSTR1 P30872 1/20 0.36
SSTR2 P30874 1/20 0.36
SSTR4 P31391 1/20 0.36
SSTR3 P32745 1/20 0.36
SSTR5 P35346 1/20 0.36
BCHE P06276 2/20 0.35
ACHE P22303 1/20 0.35
TACR1 P25103 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14616679 1.00 PDPK1 (0.40) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL18328626 1.00 PDPK1 (0.40) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL15502202 0.96 PDPK1 (0.41) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL16769165 0.96 PDPK1 (0.41) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL10120663 0.96 PDPK1 (0.41) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL15871630 0.96 PDPK1 (0.41) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL15502118 0.96 PDPK1 (0.41) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL16837354 0.91 PDPK1 (0.40) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL2600119 0.91 PDPK1 (0.40) PDPK1MTORSLC6A2TNFTACR2
SCHEMBL17522743 0.91 PDPK1 (0.40) PDPK1MTORSLC6A2TNFTACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9150557-B1 Compositions and methods for the treatment of hyperglycemia CELLIX BIO PRIVATE LIMITED (IN) 2015-10-06 US disclosed