Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22540532 | 1.00 | CA12 (0.48) | CA12CA9CA1CA2MGLL | |
| SCHEMBL16564665 | 1.00 | CA12 (0.48) | CA12CA9CA1CA2MGLL | |
| SCHEMBL5087415 | 1.00 | CA12 (0.48) | CA12CA9CA1CA2MGLL | |
| SCHEMBL11506431 | 0.98 | CA12 (0.46) | CA12CA9CA1CA2MGLL | |
| SCHEMBL8431297 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL | |
| SCHEMBL11343070 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL | |
| SCHEMBL4163491 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL | |
| SCHEMBL4155109 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL | |
| SCHEMBL2482724 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL | |
| SCHEMBL1742678 | 0.95 | CA12 (0.52) | CA12CA9CA1CA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9500775-B2 | Actinically-crosslinkable amphiphilic prepolymers | NOVARTIS AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-9151873-B2 | Actinically-crosslinkable amphiphilic prepolymers | NOVARTIS AG (CH) | 2015-10-06 | — | — | US | disclosed |