Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | BCL3 | P20749 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17142435 | 0.98 | EPHX2 (0.48) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17142872 | 0.97 | EPHX2 (0.47) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17148153 | 0.94 | EPHX2 (0.49) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17142947 | 0.93 | KMT2A (0.46) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17142605 | 0.93 | KMT2A (0.48) | KMT2ALMNAPOLBMAPTKDM4E | |
| SCHEMBL17142411 | 0.92 | NAMPT (0.47) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17143178 | 0.92 | KMT2A (0.46) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17143102 | 0.92 | BCL3 (0.51) | KMT2AEPHX2LMNAKDM4EBCL3 | |
| SCHEMBL17142414 | 0.92 | KMT2A (0.46) | KMT2AEPHX2LMNAPOLBMAPT | |
| SCHEMBL17143136 | 0.92 | KMT2A (0.45) | KMT2AEPHX2LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884063-B2 | Amido-substituted azole compounds | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-02-06 | — | — | US | disclosed |
| WO-2015150449-A2 | AMIDO-SUBSTITUTED AZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-10-08 | — | — | WO | disclosed |