Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | THPO | P40225 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928997 | 0.81 | MAPT (0.43) | NFKB1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29929578 | 0.81 | MAPT (0.43) | NFKB1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29929152 | 0.81 | MAPT (0.43) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL29928920 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL6694400 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL29900892 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL2524109 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL29584417 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL29772022 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E | |
| Rottlerin SCHEMBL1537089 | 0.79 | KDM4E (1.00) | NFKB1MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150283114-A1 | PKC Delta Inhibitors for use as Therapeutics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-08 | — | — | US | disclosed |