Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.61 |
| ▸ | CNR2 | P34972 | 6/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17142174 | 1.00 | CNR1 (0.61) | CNR1CNR2CA1CA2PTGS2 | |
| SCHEMBL17142180 | 1.00 | CNR1 (0.61) | CNR1CNR2CA1CA2PTGS2 | |
| SCHEMBL17142173 | 1.00 | CNR1 (0.61) | CNR1CNR2CA1CA2PTGS2 | |
| SCHEMBL17142183 | 1.00 | CNR1 (0.61) | CNR1CNR2CA1CA2PTGS2 | |
| SCHEMBL17142293 | 0.91 | CNR1 (0.60) | CNR1CNR2CA1CA2PDE5A | |
| SCHEMBL17142291 | 0.91 | CNR1 (0.60) | CNR1CNR2CA1CA2PDE5A | |
| SCHEMBL17142290 | 0.91 | CNR1 (0.60) | CNR1CNR2CA1CA2PDE5A | |
| SCHEMBL17150853 | 0.89 | CNR1 (0.61) | CNR1CNR2CA1CA2PDE5A | |
| SCHEMBL17150811 | 0.88 | CNR1 (0.48) | CNR1CNR2PTGS2PDE5A | |
| SCHEMBL17142196 | 0.88 | CNR1 (0.53) | CNR1CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015152550-A1 | 4,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXIMIDAMIDE DERIVATIVES CONTAINING SULFUR GROUPS, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | HANMI PHARM. CO., LTD. (KR) | 2015-10-08 | — | — | WO | disclosed |