Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.79 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.79 |
| ▸ | NAMPT | P43490 | 9/20 | 0.79 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.79 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.79 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.79 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.79 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.79 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.79 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.79 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.79 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.79 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tucidinostat SCHEMBL13815849 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| SCHEMBL5500152 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| SCHEMBL30267913 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| Tucidinostat SCHEMBL29813059 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| Tucidinostat SCHEMBL4483082 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| Tucidinostat SCHEMBL29350211 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| SCHEMBL8057949 | 0.88 | HDAC1 (1.00) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| SCHEMBL24372333 | 0.81 | HDAC1 (0.80) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| Tucidinostat SCHEMBL31697749 | 0.81 | HDAC1 (0.85) | HDAC1HDAC3HDAC2NAMPTNCOR2 | |
| Tucidinostat SCHEMBL30497063 | 0.80 | HDAC1 (0.84) | HDAC1HDAC3HDAC2NAMPTNCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284360-A1 | AMIDE DERIVATIVES OF ANILINE-RELATED COMPOUNDS AND COMPOSITIONS THEREOF | C & C BIOPHARMA LLC (US) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284360-A1 | AMIDE DERIVATIVES OF ANILINE-RELATED COMPOUNDS AND COMPOSITIONS THEREOF | AADAC, AAAS, NAT1 | HDAC1 266/4885HDAC3 120/4885HDAC2 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.