Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 1.00 |
| ▸ | ESR2 | Q92731 | 18/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | PLD2 | O14939 | 1/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.65 |
| ▸ | C5 | P01031 | 1/20 | 0.65 |
| ▸ | FYN | P06241 | 1/20 | 0.65 |
| ▸ | PGR | P06401 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24654407 | 0.99 | ESR1 (0.98) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL3743164 | 0.94 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3807019 | 0.93 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL7517965 | 0.93 | ESR1 (0.98) | ESR1ESR2MEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7942899 | 0.92 | ESR1 (0.98) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL21906803 | 0.91 | ESR1 (0.83) | ESR1ESR2 | |
| SCHEMBL24611101 | 0.91 | ESR1 (0.83) | ESR1ESR2 | |
| SCHEMBL5420295 | 0.91 | ESR1 (0.89) | ESR1ESR2MEN1ALDH1A1LMNA | |
| SCHEMBL12308318 | 0.91 | ESR1 (0.89) | ESR1ESR2MEN1ALDH1A1LMNA | |
| Arzoxifene SCHEMBL285277 | 0.91 | ESR1 (1.00) | ESR1ESR2MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117811787-B | Information configuration method, device, equipment and storage medium | 中科驭数（北京）科技有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-117811787-A | Information configuration method, device, equipment and storage medium | 中科驭数（北京）科技有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230061229-A1 | SMART WOUND DRESSINGS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2023-03-02 | — | — | US | disclosed |
| EP-4084834-A1 | SMART WOUND DRESSINGS | Inteligels Ltd. (IL) | 2022-11-09 | — | — | EP | disclosed |
| CN-111297827-B | Folate-modified nano preparation containing CCL19 recombinant expression gene and preparation method and application thereof | 四川大学 | 2022-05-24 | — | — | CN | disclosed |
| EP-3192795-B1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | UNIV ILLINOIS (US) | 2020-12-02 | — | — | EP | disclosed |
| US-10464930-B2 | Compositions and methods for treating estrogen-related medical disorders | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-11-05 | — | — | US | disclosed |
| EP-3192795-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | The Board of Trustees of the University of Illionis (US) | 2017-07-19 | — | — | EP | disclosed |
| US-20170114052-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-04-27 | — | — | US | disclosed |
| US-20170114052-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-04-27 | — | — | US | disclosed |
| US-20150284357-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-08 | — | — | US | disclosed |
| US-20150284357-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464930-B2 | Compositions and methods for treating estrogen-related medical disorders | HSD17B11, CYP19A1, ESR1 | ESR1 3/4885ESR2 5/4885MEN1 781/4885 |
| US-20150284357-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | HSD17B11, CYP19A1, ESR1 | ESR1 3/4885ESR2 5/4885MEN1 781/4885 |
| US-20170114052-A1 | COMPOSITIONS AND METHODS FOR TREATING ESTROGEN-RELATED MEDICAL DISORDERS | HSD17B11, CYP19A1, ESR1 | ESR1 3/4885ESR2 5/4885MEN1 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.