Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610543 | 0.78 | TSHR (0.39) | SLC1A3SLC1A2SLC1A1ANPEPERAP2 | |
| SCHEMBL11470552 | 0.78 | HTR2A (0.33) | — | |
| SCHEMBL30553335 | 0.78 | PLA2G1B (0.37) | PLA2G1BPLA2G2AALDH1A1TSHR | |
| SCHEMBL12498853 | 0.78 | — | — | |
| SCHEMBL1618810 | 0.78 | ANPEP (0.48) | ANPEPERAP2ERAP1ALDH1A1TSHR | |
| SCHEMBL135889 | 0.78 | ANPEP (0.48) | ANPEPERAP2ERAP1ALDH1A1TSHR | |
| SCHEMBL4624001 | 0.78 | — | — | |
| SCHEMBL2637015 | 0.78 | — | — | |
| SCHEMBL130457 | 0.78 | ANPEP (0.48) | ANPEPERAP2ERAP1ALDH1A1TSHR | |
| SCHEMBL5886361 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768966-B1 | COUMPOUNDS AND METHODS FOR INHIBITING THE INTERACTION OF BCL PROTEINS WITH BINDING PARTNERS | INFINITY DISCOVERY INC (US) | 2012-03-07 | — | — | EP | disclosed |