Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 9/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17172168 | 0.88 | CYP19A1 (0.46) | CYP19A1ABL1CCR6KCNH2SCN5A | |
| SCHEMBL17172219 | 0.88 | NPY5R (0.42) | CYP3A4CYP2C9CYP2C19ABL1CCR6 | |
| SCHEMBL17157378 | 0.87 | CYP19A1 (0.44) | CYP19A1CYP3A4CYP2C9CYP2C19ABL1 | |
| SCHEMBL17172204 | 0.85 | CYP19A1 (0.45) | CYP19A1CYP3A4CYP2C9CYP2C19ABL1 | |
| SCHEMBL7713437 | 0.82 | CYP19A1 (0.67) | CYP19A1ABL1CCR6KCNH2NPY2R | |
| SCHEMBL17172312 | 0.82 | CYP3A4 (0.37) | CYP19A1CYP3A4CYP2C9CYP2C19ABL1 | |
| SCHEMBL17172209 | 0.82 | CYP19A1 (0.66) | CYP19A1CYP3A4 | |
| SCHEMBL17172230 | 0.81 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19ABL1KCNH2 | |
| SCHEMBL17157426 | 0.81 | CYP3A4 (0.45) | CYP3A4CYP2C9CYP2C19ABL1KCNH2 | |
| SCHEMBL17172335 | 0.79 | ABL1 (0.38) | CYP3A4CYP2C9CYP2C19ABL1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-10-18 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944664-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167300-B2 | Metalloenzyme inhibitor compounds as fungicides | GPX1, POR, MGAM | CYP19A1 63/4885CYP3A4 89/4885CYP2C9 68/4885 |
| US-20150291632-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | CYP19A1 63/4885CYP3A4 89/4885CYP2C9 68/4885 |
| US-20180298038-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | CYP19A1 63/4885CYP3A4 89/4885CYP2C9 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.