Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 13/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17171892 | 0.88 | ABL1 (0.41) | SCN5AABL1PRMT6KCNH2CCR6 | |
| SCHEMBL17171872 | 0.88 | ABL1 (0.45) | SCN5AABL1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL17171870 | 0.87 | AKR1C2 (0.40) | SCN5AABL1PRMT6KCNH2CCR6 | |
| SCHEMBL17171970 | 0.87 | ALOX5AP (0.43) | ABL1CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL17171969 | 0.87 | SCN5A (0.42) | SCN5AABL1KCNH2 | |
| SCHEMBL17171902 | 0.86 | ABL1 (0.43) | SCN5AABL1CYP11B1CYP11B2PRMT6 | |
| SCHEMBL17171962 | 0.86 | CYP11B1 (0.38) | SCN5ACYP11B1CYP11B2CYP3A4 | |
| SCHEMBL17171964 | 0.86 | CACNA1B (0.44) | SCN5ACYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL17185897 | 0.84 | ABL1 (0.41) | SCN5AABL1PRMT6KCNH2CCR6 | |
| SCHEMBL17159520 | 0.84 | ABL1 (0.41) | SCN5AABL1PRMT6KCNH2CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180290998-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2018-10-11 | — | — | US | disclosed |
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957252-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2017-08-17 | — | — | US | disclosed |
| US-9663491-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663491-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| US-9663491-B2 | Metalloenzyme inhibitor compounds as fungicides | DOW AGROSCIENCES LLC (US) | 2017-05-30 | — | — | US | disclosed |
| EP-3131400-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | Dow AgroSciences LLC (US) | 2017-02-22 | — | — | EP | disclosed |
| WO-2015160664-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160664-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-10-22 | — | — | WO | disclosed |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | DOW AGROSCIENCES LLC | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180290998-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | SCN5A 959/4885ABL1 474/4885CYP11B1 42/4885 |
| US-20150291557-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | SCN5A 959/4885ABL1 474/4885CYP11B1 42/4885 |
| US-20170233369-A1 | METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES | GPX1, POR, MGAM | SCN5A 959/4885ABL1 474/4885CYP11B1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.