Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1249244 | 1.00 | TSHR (0.61) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1088757 | 0.98 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2492854 | 0.98 | TSHR (0.64) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL5272746 | 0.94 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL28988329 | 0.91 | TSHR (0.57) | TSHRDAONAPRTCES2CES1 | |
| Terephthalic Acid SCHEMBL9063579 | 0.91 | TSHR (0.57) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28890058 | 0.91 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8503046 | 0.89 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL8502658 | 0.89 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29078253 | 0.89 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450931-B2 | Process for minimizing electromigration in an electronic device | DOW CORNING CORPORATION (US) | 2013-05-28 | — | — | US | claimed |
| EP-1880416-B1 | PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE | DOW CORNING (US) | 2012-01-18 | — | — | EP | claimed |
| JP-4602970-B2 | — | — | 2010-12-22 | — | — | JP | claimed |
| EP-1597332-B1 | CONDUCTIVE ADHESIVE COMPOSITIONS WITH ELECTRICAL STABILITY AND GOOD IMPACT RESISTANCE FOR USE IN ELECTRONICS DEVICES | NAT STARCH CHEM INVEST (US) | 2008-05-07 | — | — | EP | claimed |
| US-20080054806-A1 | Process for Minimizing Electromigration in an Electronic Device | DOW CORNING CORPORATION | 2008-03-06 | — | — | US | claimed |
| EP-1880416-A1 | PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE | Dow Corning Corporation (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006122025-A1 | PROCESS FOR MINIMIZING ELECTROMIGRATION IN AN ELECTRONIC DEVICE | DOW CORNING CORPORATION (US) | 2006-11-16 | — | — | WO | claimed |
| US-7108806-B2 | Mixing epoxy resin, amine, filler, corrosion inhibitor and oxygen scavenger, imidazole curing agent and solvent | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2006-09-19 | — | — | US | claimed |
| EP-1597332-A1 | CONDUCTIVE ADHESIVE COMPOSITIONS WITH ELECTRICAL STABILITY AND GOOD IMPACT RESISTANCE FOR USE IN ELECTRONICS DEVICES | National Starch and Chemical Investment Holding Corporation (US) | 2005-11-23 | — | — | EP | claimed |
| WO-2004078870-A1 | CONDUCTIVE ADHESIVE COMPOSITIONS WITH ELECTICAL STABILITY AND GOOD IMPACT RESISTANCE FOR USE IN ELECTRONICS DEVICES | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2004-09-16 | — | — | WO | claimed |
| US-20040169162-A1 | Conductive materials with electrical stability and good impact resistance for use in electronics devices | HENKEL AG & CO. KGAA (DE) | 2004-09-02 | — | — | US | claimed |
| EP-1032038-A2 | Conductive and resitive material with electrical stability for use in electronics devices | National Starch and Chemical Investment Holding Corporation (US) | 2000-08-30 | — | — | EP | claimed |
| US-4051066-A | Corrosion-inhibiting rubber and methods of preparation | NORTHERN INSTRUMENTS CORPORATION (US) | 1977-09-27 | — | — | US | claimed |
| CN-107001216-B | Intermediates and methods for preparing sandalwood oil building blocks | 弗门尼舍有限公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-3227255-B1 | INTERMEDIATES AND PROCESS FOR THE PREPARATION OF SANDALWOOD OIL BUILDING BLOCKS | FIRMENICH & CIE (CH) | 2018-11-07 | — | — | EP | disclosed |
| US-9879203-B2 | Intermediates and process for the preparation of sandalwood oil building blocks | FIRMENICH SA (CH) | 2018-01-30 | — | — | US | disclosed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |
| US-4051066-A | Corrosion-inhibiting rubber and methods of preparation | NORTHERN INSTRUMENTS CORPORATION (US) | 1977-09-27 | — | — | US | disclosed |