Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | CPA3 | P15088 | 3/20 | 0.46 |
| ▸ | CPA1 | P15085 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716480 | 1.00 | CYP1A2 (0.52) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL12493787 | 0.88 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL12493782 | 0.88 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6789635 | 0.88 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL6789634 | 0.88 | CYP1A2 (0.59) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL27399826 | 0.85 | CYP1A2 (0.55) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL7324477 | 0.82 | CYP1A2 (0.48) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL7324462 | 0.82 | CYP1A2 (0.48) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL12494343 | 0.81 | MME (0.51) | CYP1A2MME | |
| SCHEMBL12494345 | 0.81 | MME (0.51) | CYP1A2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |
| EP-1697386-B1 | ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES | GEN ELECTRIC (US) | 2007-10-10 | — | — | EP | claimed |