Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599063 | 0.80 | MEN1 (0.44) | XDHMEN1KMT2A | |
| SCHEMBL17165094 | 0.73 | — | — | |
| SCHEMBL4219276 | 0.59 | ADORA2A (0.34) | XDH | |
| SCHEMBL29547282 | 0.59 | ADORA2A (0.34) | XDH | |
| Hydrochloric Acid SCHEMBL30378653 | 0.58 | ADORA2A (0.33) | XDH | |
| Hydrochloric Acid SCHEMBL30561516 | 0.58 | ADORA2A (0.33) | XDH | |
| SCHEMBL12680365 | 0.58 | ADORA1 (0.52) | MEN1KMT2A | |
| SCHEMBL15785416 | 0.57 | PARP1 (0.37) | — | |
| SCHEMBL22057623 | 0.55 | KMT2A (0.56) | MEN1KMT2A | |
| SCHEMBL22585445 | 0.55 | KMT2A (0.42) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015157125-A1 | THERAPUETIC USES OF SELECTED PYRAZOLOPYRIMIDINE COMPOUNDS WITH ANTI-MER TYROSINE KINASE ACTIVITY | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2015-10-15 | — | — | WO | disclosed |