Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C2B | O00750 | 19/20 | 0.81 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282281 | 0.90 | PIK3C2B (0.78) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL15022730 | 0.90 | PIK3C2B (0.81) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1281869 | 0.90 | PIK3C2B (1.00) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1281001 | 0.90 | PIK3C2B (1.00) | PIK3C2BPIK3CDPIK3CBPIK3R1 | |
| SCHEMBL1281608 | 0.90 | PIK3C2B (0.78) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1280582 | 0.90 | PIK3C2B (0.81) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL27903800 | 0.88 | PIK3C2B (0.75) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1280830 | 0.87 | PIK3C2B (0.75) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1688063 | 0.87 | PIK3C2B (0.74) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG | |
| SCHEMBL1688084 | 0.87 | PIK3C2B (0.74) | PIK3C2BPIK3CDPIK3CBPIK3R1PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156797-B2 | Benzimidazole derivatives as PI3 kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2015-10-13 | — | — | US | disclosed |