Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3758485 | 0.95 | BRAF (1.00) | BRAF | |
| SCHEMBL9909792 | 0.93 | BRAF (1.00) | BRAFMAPK14 | |
| SCHEMBL3173386 | 0.91 | BRAF (0.81) | BRAFMAPK14 | |
| SCHEMBL3762306 | 0.90 | BRAF (1.00) | BRAFMAPK14 | |
| SCHEMBL2935423 | 0.89 | BRAF (0.89) | BRAFMAPK14 | |
| SCHEMBL17407180 | 0.87 | BRAF (0.80) | BRAFMAPK14 | |
| SCHEMBL3266961 | 0.86 | BRAF (1.00) | BRAFMAPK14 | |
| SCHEMBL3758444 | 0.84 | BRAF (1.00) | BRAFMAPK14 | |
| SCHEMBL12434325 | 0.84 | BRAF (0.79) | BRAFMAPK14 | |
| SCHEMBL3191862 | 0.84 | BRAF (1.00) | BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155737-B2 | Pyrido[2,3-B]pyrazin-8-substituted compounds and their use | INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (THE) (GB) | 2015-10-13 | — | — | US | disclosed |