Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455376 | 0.86 | ABL1 (0.38) | PIM1AKT2ABL1KITEPHX2 | |
| SCHEMBL1454005 | 0.85 | PIM1 (0.35) | PIM1AKT2ABL1KIT | |
| SCHEMBL1455165 | 0.85 | PIM1 (0.35) | PIM1AKT2ABL1KITEPHX2 | |
| SCHEMBL1455238 | 0.85 | PIM1 (0.37) | PIM1AKT2ABL1KITEPHX2 | |
| SCHEMBL1454621 | 0.84 | PIM1 (0.38) | PIM1AKT2ABL1KITEPHX2 | |
| SCHEMBL1455017 | 0.84 | PIM1 (0.35) | PIM1AKT2ABL1KIT | |
| SCHEMBL1454931 | 0.84 | PIM1 (0.37) | PIM1AKT2ABL1KITEPHX2 | |
| SCHEMBL1454647 | 0.84 | ABL1 (0.35) | PIM1AKT2ABL1KITKDR | |
| SCHEMBL1455175 | 0.83 | BRAF (0.37) | — | |
| SCHEMBL1454064 | 0.83 | ABL1 (0.37) | PIM1AKT2ABL1KITEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-01-18 | — | — | EP | disclosed |