Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 6/20 | 0.61 |
| ▸ | BDNF | P23560 | 3/20 | 0.61 |
| ▸ | PTN | P21246 | 2/20 | 0.61 |
| ▸ | HPSE | Q9Y251 | 7/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | BMP2 | P12643 | 2/20 | 0.48 |
| ▸ | VEGFA | P15692 | 2/20 | 0.48 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.48 |
| ▸ | SHH | Q15465 | 2/20 | 0.48 |
| ▸ | PF4 | P02776 | 2/20 | 0.47 |
| ▸ | IFNG | P01579 | 1/20 | 0.47 |
| ▸ | CCL2 | P13500 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | BMP6 | P22004 | 1/20 | 0.47 |
| ▸ | CCL11 | P51671 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.47 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17167238 | 0.96 | MDK (0.57) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL18914908 | 0.93 | MDK (0.64) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167241 | 0.92 | MDK (0.56) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167239 | 0.89 | MDK (0.55) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167701 | 0.86 | MDK (0.59) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167223 | 0.86 | MDK (0.54) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167191 | 0.86 | MDK (0.56) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167254 | 0.84 | MDK (0.53) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167240 | 0.84 | F10 (0.51) | MDKBDNFPTNHPSEF10 | |
| SCHEMBL17167244 | 0.81 | F10 (0.49) | MDKBDNFPTNHPSEF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152279-A9 | Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 | UNIVERSITY OF LIVERPOOL (GB) | 2017-06-01 | — | — | US | disclosed |
| US-20150291644-A1 | Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 | VICTORIA LINK LTD (NZ) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291644-A1 | Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 | BACE1, BACE2, APP | MDK 4339/4885BDNF 121/4885PTN 3312/4885 |
| US-20170152279-A9 | Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 | BACE1, BACE2, APP | MDK 4339/4885BDNF 121/4885PTN 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.