SCHEMBL17167246

SCHEMBL17167246

O=C(CCO)NCCCCCCOC1OC(C(=O)O)C(OC2CC(O)C(OC3OC(C(=O)O)C(OC4OC(COS(=O)(=O)O)C(O)C(O)C4NS(=O)O)C(O)C3OS(=O)(=O)O)C(COS(=O)(=O)O)O2)C(O)C1OS(=O)(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.46
▸ MDK P21741 4/20 0.43
▸ BDNF P23560 3/20 0.43
▸ PTN P21246 2/20 0.43
▸ CXCL12 P48061 2/20 0.39
▸ CXCL10 P02778 1/20 0.39
▸ CXCL8 P10145 1/20 0.39
▸ CCL2 P13500 1/20 0.39
▸ CCL5 P13501 1/20 0.39
▸ HPSE Q9Y251 9/20 0.38
▸ FGF2 P09038 5/20 0.37
▸ FGF1 P05230 3/20 0.37
▸ BMP2 P12643 1/20 0.35
▸ VEGFA P15692 1/20 0.35
▸ SHH Q15465 1/20 0.35
▸ SERPINC1 P01008 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907661 0.93 F10 (0.54) F10MDKBDNFPTNCXCL12
SCHEMBL17167243 0.90 F10 (0.56) F10MDKBDNFPTNCXCL12
SCHEMBL18907660 0.89 F10 (0.52) F10MDKBDNFPTNCXCL12
SCHEMBL17167240 0.87 F10 (0.51) F10MDKBDNFPTNHPSE
SCHEMBL17167244 0.83 F10 (0.49) F10MDKBDNFPTNCXCL12
SCHEMBL17167241 0.83 MDK (0.56) F10MDKBDNFPTNCXCL12
SCHEMBL17167242 0.82 MDK (0.40) F10MDKBDNFPTNCXCL12
SCHEMBL17167239 0.80 MDK (0.55) F10MDKBDNFPTNCXCL12
SCHEMBL17167701 0.79 MDK (0.59) F10MDKBDNFPTNCXCL12
SCHEMBL17167256 0.78 F10 (0.47) F10MDKBDNFPTNCXCL12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP F10 3347/4885MDK 4339/4885BDNF 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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