SCHEMBL17167255

SCHEMBL17167255

CCC1OC(OC2C(C(=O)O)OC(OC3C(O)CC(OC4C(C(=O)O)OC(OCCCCCCNC(=O)CCOCCOCCOCCNC(=O)CCCCCCCNC(=O)CCOCC(C)(C)CC)C(O)C4O)OC3COS(=O)(=O)O)C(O)C2O)C(NS(=O)(=O)O)C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.44
MDK P21741 6/20 0.43
BDNF P23560 3/20 0.41
PTN P21246 2/20 0.41
HPSE Q9Y251 12/20 0.38
PF4 P02776 1/20 0.35
FGF1 P05230 3/20 0.34
FGF2 P09038 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167256 0.94 F10 (0.47) F10MDKBDNFPTNHPSE
SCHEMBL17167261 0.93 MDK (0.45) F10MDKBDNFPTNHPSE
SCHEMBL17167254 0.88 MDK (0.53) F10MDKBDNFPTNHPSE
SCHEMBL17167244 0.88 F10 (0.49) F10MDKBDNFPTNHPSE
SCHEMBL17167195 0.85 F10 (0.51) F10MDKBDNFPTNHPSE
SCHEMBL17167223 0.84 MDK (0.54) F10MDKBDNFPTNHPSE
SCHEMBL17167240 0.84 F10 (0.51) F10MDKBDNFPTNHPSE
SCHEMBL17167203 0.82 MDK (0.39) F10MDKBDNFPTNHPSE
SCHEMBL17167257 0.82 MDK (0.49) F10MDKBDNFPTNHPSE
SCHEMBL18907660 0.81 F10 (0.52) F10MDKBDNFPTNHPSE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 UNIVERSITY OF LIVERPOOL (GB) 2017-06-01 US disclosed
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP F10 3347/4885MDK 4339/4885BDNF 121/4885
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP F10 3347/4885MDK 4339/4885BDNF 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.