Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169053 | 0.90 | BACE1 (0.77) | BACE1BACE2 | |
| SCHEMBL18636982 | 0.89 | BACE1 (0.85) | BACE1BACE2 | |
| SCHEMBL18636705 | 0.88 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL17169262 | 0.87 | BACE1 (0.75) | BACE1BACE2 | |
| SCHEMBL17169059 | 0.87 | BACE1 (0.76) | BACE1BACE2 | |
| SCHEMBL17169054 | 0.86 | BACE1 (0.83) | BACE1BACE2 | |
| SCHEMBL4078021 | 0.84 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL4078652 | 0.81 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL4083464 | 0.81 | BACE1 (0.81) | BACE1BACE2 | |
| SCHEMBL4083288 | 0.80 | BACE1 (0.84) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015156421-A1 | DIHYDROTHIAZINE AND DIHYDROOXAZINE DERIVATIVES HAVING BACE1 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2015-10-15 | — | — | WO | disclosed |