Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2991114 | 0.99 | KMT2A (0.57) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1726019 | 0.86 | KMT2A (0.66) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL13198964 | 0.86 | KMT2A (0.49) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1717639 | 0.86 | MAPT (0.57) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1717643 | 0.86 | MAPT (0.57) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1716666 | 0.84 | KMT2A (0.62) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL2977848 | 0.83 | KMT2A (0.61) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1717615 | 0.83 | KMT2A (0.61) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1717285 | 0.82 | KMT2A (0.60) | KMT2AMEN1NPC1MAPTKDM4E | |
| SCHEMBL1716675 | 0.82 | KMT2A (0.61) | KMT2AMEN1NPC1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656373-B1 | DERIVATIVES OF 2-ACYLAMINO-4-PHENYLTHIAZOLE, PREPARATION METHOD THEREOF AND USE OF SAME AS CHEMOKINEANTAGONISTS | SANOFI SA (FR) | 2012-01-18 | — | — | EP | disclosed |
| EP-1656373-A2 | DERIVATIVES OF 2-ACYLAMINO-4-PHENYLTHIAZOLE, PREPARATION METHOD THEREOF AND USE OF SAME AS CHEMOKINEANTAGONISTS | Sanofi-Aventis (FR) | 2006-05-17 | — | — | EP | disclosed |
| WO-2004096798-A2 | DERIVATIVES OF 2-ACYLAMINO-4-PHENYLTHIAZOLE, PREPARATION METHOD THEREOF AND USE OF SAME AS CHEMOKINE ANTAGONISTS | SANOFI-AVENTIS (FR) | 2004-11-11 | — | — | WO | disclosed |