Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.69 |
| ▸ | ACE | P12821 | 4/20 | 0.69 |
| ▸ | MMEL1 | Q495T6 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17169876 | 0.92 | MME (0.57) | MMEACEMMEL1 | |
| SCHEMBL28450662 | 0.90 | MME (0.77) | MMEACEMMEL1 | |
| SCHEMBL28450664 | 0.90 | MME (0.77) | MMEACEMMEL1 | |
| SCHEMBL7436015 | 0.87 | MME (0.76) | MMEACEMMEL1 | |
| SCHEMBL28456484 | 0.87 | MME (0.76) | MMEACEMMEL1 | |
| SCHEMBL22585406 | 0.86 | MME (0.74) | MMEACEMMEL1 | |
| SCHEMBL22556618 | 0.85 | MME (0.80) | MMEACEMMEL1 | |
| SCHEMBL22556619 | 0.85 | MME (0.80) | MMEACEMMEL1 | |
| SCHEMBL3605256 | 0.84 | MME (0.71) | MMEACEMMEL1 | |
| SCHEMBL17169811 | 0.83 | MME (0.76) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015154673-A1 | NOVEL PRODRUGS AND COMBINATIONS FOR TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASES | WANG ZHAOYIN (CN) | 2015-10-15 | — | — | WO | disclosed |