Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737382 | 0.88 | — | — | |
| SCHEMBL13647218 | 0.84 | DPP4 (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL23565822 | 0.84 | DPP4 (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL22329117 | 0.84 | PIK3CD (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL24789582 | 0.84 | DPP4 (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL24790013 | 0.84 | DPP4 (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL18960693 | 0.84 | DPP4 (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL18842700 | 0.84 | PIK3CD (0.32) | DPP4DPP8DPP9 | |
| SCHEMBL24191658 | 0.79 | — | — | |
| SCHEMBL23365924 | 0.78 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388196-B2 | Thiazole derivatives as alpha 7 nAChR modulators | LUPIN LIMITED (IN) | 2016-07-12 | — | — | US | disclosed |
| US-20150291617-A1 | Thiazole Derivatives as Alpha 7 nAChR Modulators | LUPIN LIMITED (IN) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291617-A1 | Thiazole Derivatives as Alpha 7 nAChR Modulators | CHRNA7, CHRM1, CHRM2 | DPP4 1642/4885DPP8 1630/4885DPP9 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.