SCHEMBL17179986

SCHEMBL17179986

O=Cc1cccc(C(=O)c2ccccc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.50
AKR1C3 P42330 1/20 0.50
MAPT P10636 2/20 0.47
GAA P10253 2/20 0.47
MAPK1 P28482 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 2/20 0.45
TDP1 Q9NUW8 2/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TRIM24 O15164 1/20 0.44
TRIM33 Q9UPN9 1/20 0.44
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43
TLR6 Q9Y2C9 1/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1004343 0.85 AKR1C3 (0.57) AKR1C3MAPTGAAMAPK1KDM4E
SCHEMBL11176226 0.84 AKR1C3 (0.48) AKR1C3MAPTGAAMAPK1KDM4E
SCHEMBL9774817 0.84 AKR1C3 (0.52) AKR1C3MAPTGAAMAPK1ALDH1A1
Hydrazine SCHEMBL28440641 0.83 ERN1 (0.44) ERN1MAPTGAATRIM24TRIM33
SCHEMBL7606293 0.82 AKR1C3 (0.50) AKR1C3MAPTGAAMAPK1ALDH1A1
SCHEMBL6936487 0.81 MAPT (0.46) AKR1C3MAPTGAAMAPK1KDM4E
SCHEMBL6447089 0.81 MAPT (0.46) AKR1C3MAPTGAAMAPK1KDM4E
SCHEMBL348314 0.81 ERN1 (0.57) ERN1KDM4EALOX15HSD17B10ALDH1A1
SCHEMBL29357851 0.81 ERN1 (0.57) ERN1KDM4EALOX15HSD17B10ALDH1A1
Water SCHEMBL17627596 0.79 ERN1 (0.55) ERN1KDM4EALOX15HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459296-B (ethylene, vinyl acetal) copolymers and their use in lithographic printing plate precursors 爱克发有限公司 2020-07-10 CN disclosed
EP-2933278-B1 (Ethylene, vinyl acetal) copolymers and their use in lithographic printing plate precursors AGFA NV (BE) 2018-08-22 EP disclosed
US-20170101496-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA GRAPHICS NV (BE) 2017-04-13 US disclosed
CN-106459296-A (ethylene, vinyl acetal) copolymers and their use in lithographic printing plate precursors 爱克发印艺公司 2017-02-22 CN disclosed
WO-2015158566-A1 (ETHYLENE, VINYL ACETAL) COPOLYMERS AND THEIR USE IN LITHOGRAPHIC PRINTING PLATE PRECURSORS AGFA GRAPHICS NV (BE) 2015-10-22 WO disclosed
EP-2933278-A1 (Ethylene, vinyl acetal) copolymers and their use in lithographic printing plate precursors AGFA GRAPHICS NV (BE) 2015-10-21 EP disclosed