Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17180793 | 0.91 | EIF4E (0.75) | EIF4E | |
| SCHEMBL17180820 | 0.89 | EIF4E (0.67) | EIF4E | |
| SCHEMBL17180744 | 0.88 | EIF4E (0.75) | EIF4E | |
| SCHEMBL17180703 | 0.88 | EIF4E (0.75) | EIF4E | |
| SCHEMBL17180736 | 0.88 | EIF4E (0.72) | EIF4E | |
| SCHEMBL14797312 | 0.87 | EIF4E (1.00) | EIF4E | |
| SCHEMBL17180726 | 0.86 | EIF4E (0.77) | EIF4E | |
| SCHEMBL17180735 | 0.85 | EIF4E (0.76) | EIF4E | |
| SCHEMBL17180704 | 0.84 | EIF4E (0.78) | EIF4E | |
| SCHEMBL17180779 | 0.84 | EIF4E (0.76) | EIF4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758380-B1 | BENZOIC ACID DERIVATIVES AS EIF4E INHIBITORS | HOFFMANN LA ROCHE (CH) | 2015-10-21 | — | — | EP | claimed |