Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL17181713 | 1.00 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL6394826 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL21734203 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL9420938 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL11516841 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL17181728 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL21734205 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL20591059 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL3446641 | 0.94 | TP53 (0.40) | TP53CA4CA2CA1TSHR | |
| L-Lactic Acid SCHEMBL5611217 | 0.92 | TP53 (0.38) | TP53CA4CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570066-B2 | Agricultural compositions and applications utilizing mineral compounds | RALCO NUTRITION, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180370866-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION INC (US) | 2018-12-27 | — | — | US | disclosed |
| EP-3131865-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | Ralco Nutrition, Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20150299058-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION, INC. | 2015-10-22 | — | — | US | disclosed |
| WO-2015161269-A1 | AGRICULTURAL COMPOSITIONS AND APPLICATIONS UTILIZING MINERAL COMPOUNDS | RALCO NUTRITION, INC. (US) | 2015-10-22 | — | — | WO | disclosed |