SCHEMBL17186254

SCHEMBL17186254

Nc1nc2nc(CCc3ccc(CCc4ccccc4)cc3)[nH]c2c(=O)[nH]1

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PNP P00491 10/20 0.75
FGFR1 P11362 1/20 0.56
FGFR2 P21802 1/20 0.56
BACE1 P56817 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6268526 0.99 PNP (0.77) PNPFGFR1FGFR2BACE1
Hydrochloric Acid SCHEMBL17186275 0.92 PNP (0.64) PNPFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186401 0.89 PNP (0.71) PNPFGFR1FGFR2
Hydrochloric Acid SCHEMBL17186459 0.89 PNP (0.60) PNPFGFR1FGFR2
SCHEMBL18248 0.86 PNP (1.00) PNPFGFR1FGFR2
SCHEMBL5935062 0.85 PNP (0.70) PNPFGFR1FGFR2
SCHEMBL17186616 0.84 PNP (0.61) PNPFGFR1FGFR2
SCHEMBL17186504 0.84 PNP (0.54) PNP
Hydrochloric Acid SCHEMBL17186559 0.83 PNP (0.60) PNPFGFR1FGFR2
SCHEMBL17186542 0.83 PNP (0.53) PNPFGFR1FGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131877-A1 GUANIDINE COMPOUNDS AND USE THEREOF Immunomet Therapeutics Inc. (US) 2017-02-22 EP claimed
WO-2015160220-A1 GUANIDINE COMPOUNDS AND USE THEREOF HANALL BIOPHARMA CO., LTD. (KR) 2015-10-22 WO claimed
EP-3131877-A1 GUANIDINE COMPOUNDS AND USE THEREOF Immunomet Therapeutics Inc. (US) 2017-02-22 EP disclosed
WO-2015160220-A1 GUANIDINE COMPOUNDS AND USE THEREOF HANALL BIOPHARMA CO., LTD. (KR) 2015-10-22 WO disclosed