Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5932203 | 0.97 | TSHR (0.52) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL429250 | 0.97 | TSHR (0.52) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL19262110 | 0.97 | TSHR (0.52) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL5933461 | 0.97 | TSHR (0.52) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL24336335 | 0.95 | TSHR (0.50) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL10002261 | 0.95 | MEN1 (0.56) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL237526 | 0.95 | — | — | |
| Ethylenediamine SCHEMBL27579634 | 0.95 | TSHR (0.55) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL14220380 | 0.92 | MEN1 (0.60) | TSHRCYP3A4MEN1KMT2AHTT | |
| SCHEMBL11520010 | 0.92 | MEN1 (0.60) | TSHRCYP3A4MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163112-B2 | Reactive polymer catalysts for 2-component epoxy resin systems | SIKA TECHNOLOGY AG (CH) | 2015-10-20 | — | — | US | disclosed |