Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16653876 | 0.77 | KDM4E (0.31) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL23091604 | 0.74 | PPP5C (0.31) | — | |
| SCHEMBL28157840 | 0.74 | — | — | |
| SCHEMBL29777342 | 0.74 | PPP5C (0.31) | — | |
| SCHEMBL30427247 | 0.74 | PPP5C (0.31) | — | |
| Hydrochloric Acid SCHEMBL23628632 | 0.72 | — | — | |
| SCHEMBL25661145 | 0.72 | GABRR1 (0.36) | KDM4EKMT2ACYP2D6 | |
| SCHEMBL25661144 | 0.72 | GABRR1 (0.36) | KDM4EKMT2ACYP2D6 | |
| SCHEMBL6649079 | 0.68 | — | — | |
| SCHEMBL14506020 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2933248-A1 | NOVEL RENIN INHIBITOR | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-10-21 | — | — | EP | disclosed |