SCHEMBL17189293

SCHEMBL17189293

CC1OC(c2ccc(Cl)c(Cc3ccc(O)cc3)c2)C(O)C(O)C1O

nearest known ligand 0.77

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 19/20 0.77
SLC5A1 P13866 13/20 0.77
ADRA2A P08913 1/20 0.56
SLC5A11 Q8WWX8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3438615 0.90 SLC5A2 (0.77) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18264981 0.90 SLC5A2 (0.77) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL13626820 0.90 SLC5A2 (0.78) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL28823577 0.88 SLC5A2 (0.80) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL17189188 0.87 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL14108323 0.87 SLC5A2 (1.00) SLC5A2SLC5A1
SCHEMBL17189348 0.86 SLC5A2 (0.75) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL14108388 0.86 SLC5A2 (0.75) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18573839 0.85 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL18685100 0.85 SLC5A2 (1.00) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3246324-A2 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USES THEREOF Tianjin Institute Of Pharmaceutical Research (CN) 2017-11-22 EP disclosed
EP-2933250-A1 PHENYL C-GLUCOSIDE DERIVATIVE CONTAINING DEOXYGLUCOSE STRUCTURE, PREPARATION METHOD AND USE THEREOF Tianjin Institute Of Pharmaceutical Research (CN) 2015-10-21 EP disclosed