Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | CDC25C | P30307 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17190552 | 0.99 | PPARG (0.33) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17228818 | 0.99 | PPARG (0.33) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17190554 | 0.94 | PPARG (0.35) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17190553 | 0.94 | PPARG (0.35) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17483878 | 0.93 | PPARG (0.35) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17483942 | 0.92 | CDC25A (0.36) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17483956 | 0.90 | CDC25A (0.36) | PPARGPPARAMAPTCDC25ACDC25B | |
| SCHEMBL17484032 | 0.89 | PPARG (0.34) | PPARGPPARAMAPTTP53CDC25A | |
| SCHEMBL17483876 | 0.88 | PPARG (0.34) | PPARGPPARACDC25ACDC25BCDC25C | |
| SCHEMBL17483954 | 0.87 | CDC25A (0.36) | PPARGPPARAMAPTCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20160319592-A1 | DEVICE FOR REGULATING THE PASSAGE OF LIGHT | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |