Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172257 | 0.88 | CASR (0.62) | CASR | |
| SCHEMBL926340 | 0.80 | CASR (1.00) | CASR | |
| SCHEMBL925655 | 0.80 | CASR (0.83) | CASR | |
| SCHEMBL929095 | 0.79 | CASR (0.72) | CASR | |
| SCHEMBL927030 | 0.79 | CASR (0.68) | CASR | |
| SCHEMBL926547 | 0.79 | CASR (0.72) | CASR | |
| SCHEMBL14531137 | 0.79 | CASR (0.81) | CASR | |
| SCHEMBL926103 | 0.78 | CASR (0.74) | CASR | |
| SCHEMBL926470 | 0.78 | CASR (1.00) | CASR | |
| SCHEMBL12943285 | 0.78 | CASR (0.80) | CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874765-B1 | UREA DERIVATIVES, METHODS FOR THEIR MANUFACTURE AND USES THEREOF | GALAPAGOS SAS (FR) | 2012-03-07 | — | — | EP | disclosed |
| EP-2354137-A1 | Urea derivatives, methods for their manufacture, and uses thereof | Galapagos SAS (FR) | 2011-08-10 | — | — | EP | disclosed |