Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17192283 | 0.99 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192261 | 0.99 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192259 | 0.96 | MAPT (0.42) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192265 | 0.96 | MAPT (0.38) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192252 | 0.96 | MAPT (0.40) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192275 | 0.95 | TYR (0.39) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192260 | 0.95 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192287 | 0.95 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192276 | 0.95 | MAPT (0.39) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17192267 | 0.95 | TYR (0.39) | MAPTALDH1A1KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362506-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-20160319194-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2016-11-03 | — | — | US | disclosed |
| US-20150299574-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |