Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16884109 | 1.00 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21949143 | 0.89 | IRAK4 (0.79) | IRAK4 | |
| SCHEMBL16873594 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16873596 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16873592 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL29937797 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16874178 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL16874177 | 0.88 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL24607164 | 0.80 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL24607166 | 0.80 | IRAK4 (0.69) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169252-B2 | Heteroaryl substituted nicotinamide compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | claimed |
| US-8993631-B2 | Method of treating contrast-induced nephropathy | NOVARTIS AG (CH) | 2015-03-31 | — | — | US | disclosed |