⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796373 | 0.93 | CA1 (0.43) | — | |
| SCHEMBL13125935 | 0.90 | KMT2A (0.46) | — | |
| SCHEMBL1851994 | 0.86 | — | — | |
| SCHEMBL9239028 | 0.75 | — | — | |
| SCHEMBL2342739 | 0.69 | — | — | |
| SCHEMBL918055 | 0.67 | — | — | |
| SCHEMBL21495046 | 0.67 | — | — | |
| SCHEMBL280398 | 0.67 | — | — | |
| SCHEMBL10882169 | 0.67 | — | — | |
| SCHEMBL7549489 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677559-B | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-115677559-A | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-111689927-A | Piperazinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2020-09-22 | — | — | CN | claimed |
| CN-111662280-A | Piperidinyl tetrahydrobenzothiazole oxime ether derivative and application thereof | 南开大学 | 2020-09-15 | — | — | CN | claimed |
| CN-105777773-A | Thiophene[2,3-b]quinoline derivative and synthetic method and application thereof | 浙江师范大学 | 2016-07-20 | — | — | CN | claimed |
| US-20260034093-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2026-02-05 | — | — | US | disclosed |
| EP-4626423-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-10-08 | — | — | EP | disclosed |
| US-20240358675-A1 | MULTICYCLIC COMPOUNDS AND METHODS OF USE THEREOF | SUMITOMO PHARMA AMERICA, INC. (US) | 2024-10-31 | — | — | US | disclosed |
| CN-118165002-A | Polycyclic compounds and methods of use thereof | 桑诺维恩药品公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2024119122-A1 | CDK INHIBITORS AND METHODS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| CN-115677559-B | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-115677559-B | One-step synthesis method of ondansetron intermediate tetrahydrocarbazolone | 常州兰陵制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-0843681-A1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-05-27 | — | — | EP | disclosed |
| CN-1179162-A | fused heterocyclic thiazole derivatives | YUNGJIN PHARMACEUTICLA CO LTD (KR) | 1998-04-15 | — | — | CN | disclosed |
| WO-1997003076-A1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |
| US-4257957-A | Methyl-tris-(4-hydroxycoumarin)silane | GENERAL ELECTRIC COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4238401-A | ALKANOL, HALOSILANE, 1,3-DICARBONYL CYCLIC COMPOUND, VULCANIZATION AGENTS | GENERAL ELECTRIC COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4210596-A | Silyl ethers of 1,3-dicarbonyl cyclic compounds | GENERAL ELECTRIC COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-3954984-A | ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS | RICHARDSON-MERRELL INC. (US) | 1976-05-04 | — | — | US | disclosed |
| US-3931171-A | FROM A 1,3-DIOXINONE-(4) AND AN ISOCYANATE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-06 | — | — | US | disclosed |