Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698726 | 0.72 | TDP1 (0.56) | TDP1MEN1CHRM2CHRM4CHRM5 | |
| SCHEMBL4761221 | 0.72 | TDP1 (0.56) | TDP1MEN1CHRM2CHRM4CHRM5 | |
| SCHEMBL2964186 | 0.70 | — | — | |
| SCHEMBL18427650 | 0.69 | — | — | |
| SCHEMBL11698740 | 0.69 | — | — | |
| SCHEMBL17198665 | 0.67 | PDK2 (0.32) | — | |
| SCHEMBL31103 | 0.64 | — | — | |
| SCHEMBL12310995 | 0.64 | CHRM2 (0.48) | TDP1MEN1CHRM2CHRM4CHRM5 | |
| SCHEMBL254677 | 0.64 | TDP1 (0.50) | TDP1MEN1CHRM2CHRM4CHRM5 | |
| SCHEMBL13436781 | 0.62 | CHRM2 (0.47) | TDP1MEN1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015158605-A1 | HETARYL SUBSTITUTED MALONONITRILE COMPOUNDS | BASF SE (DE) | 2015-10-22 | — | — | WO | disclosed |