⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18948730 | 0.84 | — | — | |
| SCHEMBL19145813 | 0.67 | — | — | |
| SCHEMBL10037574 | 0.64 | — | — | |
| SCHEMBL18681406 | 0.62 | — | — | |
| SCHEMBL16588476 | 0.62 | — | — | |
| SCHEMBL13464191 | 0.60 | — | — | |
| SCHEMBL3069575 | 0.60 | — | — | |
| SCHEMBL9500691 | 0.60 | — | — | |
| SCHEMBL18033867 | 0.60 | — | — | |
| SCHEMBL8595308 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10981951-B2 | Therapeutics for the treatment of glaucoma | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-04-20 | — | — | US | disclosed |
| US-10457792-B2 | Polarizing plate protective film, polarizing plate, and display device | FUJIFILM CORPORATION (JP) | 2019-10-29 | — | — | US | disclosed |
| US-10428044-B2 | 3-amino-1,5,6,7-tetrahydro-4H-indol-4-ones | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| US-10338277-B2 | Polarizing plate protective film, polarizing plate, and display | FUJIFILM CORPORATION (JP) | 2019-07-02 | — | — | US | disclosed |
| WO-2017199039-A1 | STEROID 6.7.BETA.-EPOXIDES AS CHEMICAL INTERMEDIATES | NZP UK Limited (GB) | 2017-11-23 | — | — | WO | disclosed |
| US-20170226317-A1 | POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2017-08-10 | — | — | US | disclosed |
| US-20170101391-A1 | 3-AMINO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| US-20150133491-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-05-14 | — | — | US | disclosed |
| US-8987299-B2 | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2015-03-24 | — | — | US | disclosed |
| US-8916717-B2 | Dioxaspiroketal derivatives, process for their preparation and uses thereof | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2014-12-23 | — | — | US | disclosed |
| US-20140161736-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A (IT) | 2014-06-12 | — | — | US | disclosed |
| EP-2027115-B1 | DIOXASPIROKETAL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CNR CONSIGLIO NAZ DELLE RICERCHE (IT) | 2012-01-11 | — | — | EP | disclosed |
| WO-2011012600-A1 | RING-ANNULATED DIHYDROPYRROLO[2,L-A]ISOQUINOLINES | N.V. ORGANON (NL) | 2011-02-03 | — | — | WO | disclosed |
| US-20100227919-A1 | Dioxaspiroketal Derivatives, Process for Their Preparation and Uses Thereof | CONSIGLIO NAZIONALE DELLE RICERCHE | 2010-09-09 | — | — | US | disclosed |
| EP-2181985-A1 | Antiviral Agent | SHIONOGI & CO., LTD. (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2027115-A1 | DIOXASPIROKETAL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CNR Consiglio Nazionale Delle Ricerche (IT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007132496-A1 | DIOXASPIROKETAL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USES THEREOF | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2007-11-22 | — | — | WO | disclosed |