Cloprostenol

Cloprostenol

SCHEMBL17200671

O=C(O)CCC/C=C\C[C@@H]1C(C=C[C@@H](O)COc2cccc(Cl)c2)[C@H](O)C[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 16/20 1.00
PTGER3 P43115 5/20 1.00
TBXA2R P21731 2/20 1.00
PTGER1 P34995 2/20 1.00
THRB P10828 1/20 1.00
PTGER2 P43116 1/20 1.00
ABCC4 O15439 2/20 0.84
ABCB11 O95342 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cloprostenol SCHEMBL13399778 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL15390430 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL14913508 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL29407616 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL123596 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL14913507 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL15669946 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL3364442 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL123595 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
Cloprostenol SCHEMBL3364445 1.00 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150306182-A1 FAT LOSS COMPOSITION KENNY PETER (US) 2015-10-29 US disclosed