⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23471313 | 0.73 | — | — | |
| SCHEMBL9038210 | 0.69 | — | — | |
| SCHEMBL1015818 | 0.61 | — | — | |
| SCHEMBL4999739 | 0.54 | — | — | |
| SCHEMBL17831046 | 0.53 | — | — | |
| SCHEMBL23471309 | 0.52 | — | — | |
| SCHEMBL23730768 | 0.51 | — | — | |
| SCHEMBL762235 | 0.45 | — | — | |
| SCHEMBL25964836 | 0.38 | — | — | |
| SCHEMBL3464133 | 0.36 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9657024-B2 | Substituted triazolo-pyrimidine compounds for modulating cell proliferation, differentiation and survival | STATEGICS, INC. (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150307498-A1 | SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL | THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2015-10-29 | — | — | US | disclosed |