Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.55 |
| ▸ | PDE4A | P27815 | 9/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72555 | 0.86 | PDE4D (0.73) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL70818 | 0.86 | PDE4D (0.61) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL71115 | 0.85 | PDE4D (0.71) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL71124 | 0.85 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL71310 | 0.83 | PDE4D (0.60) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL1433277 | 0.83 | CNR2 (0.48) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29733437 | 0.83 | CNR2 (0.48) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL71412 | 0.82 | PDE4D (0.55) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL71161 | 0.82 | PDE4D (0.62) | PDE4DPDE4APDE4BPDE4CPOLB | |
| SCHEMBL69648 | 0.81 | PDE4D (0.55) | PDE4DPDE4APDE4BPDE4CPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935239-B1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | SANOFI SA (FR) | 2018-08-29 | — | — | EP | disclosed |
| US-9611250-B2 | Process for preparing 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SANOFI (FR) | 2017-04-04 | — | — | US | disclosed |
| US-9611250-B2 | Process for preparing 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SANOFI (FR) | 2017-04-04 | — | — | US | disclosed |
| US-20150307474-A1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | SANOFI (FR) | 2015-10-29 | — | — | US | disclosed |
| US-20150307474-A1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | SANOFI (FR) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307474-A1 | PROCESS FOR PREPARING 4-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLORO-1-OXIDO-4-PYRIDYL)-5-METHOXYPYRIDINE-2-CARBOXAMIDE | CYP3A4, CYP4B1, CYP3A5 | PDE4D 341/4885PDE4A 364/4885PDE4B 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.