Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.68 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202118 | 1.00 | SLC2A1 (0.68) | SLC2A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL1853927 | 0.82 | SLC2A1 (0.65) | SLC2A1KMT2AMEN1HTTCYP2C9 | |
| SCHEMBL17213943 | 0.82 | SLC2A1 (0.68) | SLC2A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL17201991 | 0.81 | SLC2A1 (0.70) | SLC2A1S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL14195656 | 0.81 | SLC2A1 (0.70) | SLC2A1S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL17202209 | 0.81 | SLC2A1 (0.70) | SLC2A1S1PR5S1PR2S1PR1S1PR3 | |
| SCHEMBL17214323 | 0.80 | SLC2A1 (0.69) | SLC2A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL17214329 | 0.80 | SLC2A1 (0.69) | SLC2A1CNR1CNR2KMT2AMEN1 | |
| SCHEMBL1854400 | 0.79 | SLC2A1 (0.57) | SLC2A1KMT2AS1PR5HTR1BS1PR2 | |
| SCHEMBL23271675 | 0.78 | CNR1 (0.61) | SLC2A1CNR1CNR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015163936-A1 | BICYCLIC DERIVATIVES AS SPHINGOSINE-1 -PHOSPHATE RECEPTORS MODULATORS | ALLERGAN, INC. (US) | 2015-10-29 | — | — | WO | disclosed |